Publications Choose Therapeutic Area All Areas Cardio-renal-metabolic (1) Drug Discovery (2) Hepatobiliary (5) Neurodegenerative (1) Search Publications Found 9 Results November 2024 ABCB4/MDR2 Haploinsufficiency Predisposes Mice to Biliary Injury and Secondary Cholestasis and Defines a Translational Model of Toxic Bile Induced Hepatobiliary Injury in Human Cholangiopathy Read More November 2024 Identification and In Vitro Characterization of a Novel BSEP and ABCB4 Dual-Acting Positive Functional Modulator Targeting The Treatment of a Broad Range of Hepatobiliary Diseases Read More November 2024 Identification and in vitro characterization of novel ABCD1 positive functional modulators for the treatment of X-linked adrenoleukodystrophy Read More October 2024 A Positive Functional Modulator of ABCC6 decreases vascular calcification and improves kidney function in a rat adenine diet model Read More July 2024 Characterization of cholestasis in a knock-in BSEPE297G PFIC2 mouse model Read More March 2024 A structural and mechanistic model for BSEP dysfunction in severe cholestastic disease Read More February 2024 A class-based approach to drug discovery: mining the pharmacotherapeutic potential of the ABC transporter superfamily Read More November 2023 A knock-in BSEPE297G mouse presents with cholestasis and is a novel translational model of PFIC2 Read More 12»
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